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APX3330
APX2009 and APX2014
Phentolamine Ophthalmic Solution 0.75%
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Clinical Trials
Overview
VEGA-2 Pivotal Phase 3 Trial of Phentolamine Ophthalmic Solution 0.75% in Presbyopia
Completed
ZETA-1: Diabetic Retinopathy Phase 2 Clinical Trial for APX3330
Completed
MIRA-4: Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric Subjects
Completed
MIRA-3
Completed
MIRA-2: Reversal of Mydriasis Phase 3 Clinical Trial for Nyxol
Completed
LYNX-1: Dim Light Vision Disturbance Phase 3 Clinical Trial for Nyxol
Completed
VEGA-1: Presbyopia Phase 2 Clinical Trial for Nyxol with Low-Dose Pilocarpine
Completed
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Clinical Trials
Clinical Trials
Clinical Trials
Overview
VEGA-2 Pivotal Phase 3 Trial of Phentolamine Ophthalmic Solution 0.75% in Presbyopia
ZETA-1: Diabetic Retinopathy Phase 2 Clinical Trial for APX3330
MIRA-4: Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric Subjects
MIRA-3
MIRA-2: Reversal of Mydriasis Phase 3 Clinical Trial for Nyxol
LYNX-1: Dim Light Vision Disturbance Phase 3 Clinical Trial for Nyxol
VEGA-1: Presbyopia Phase 2 Clinical Trial for Nyxol with Low-Dose Pilocarpine
Current Trials
Recruiting
Safety and Efficacy of 0.75% Phentolamine Ophthalmic Solution in Subjects With Post-refractive Surgery Visual Disturbances
LYNX-2: Dim Light Vision Disturbance Phase 3 Clinical Trial for Nyxol in Subjects Who Have Previously Had Keratorefractive Surgery:
View Clinical Trial
Recruiting
Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia
VEGA-3: Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia:
View Clinical Trial
Completed Trials
Completed
Safety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With Presbyopia
VEGA-2 Pivotal Phase 3 Trial of Phentolamine Ophthalmic Solution 0.75% in Presbyopia:
View Clinical Trial
Completed
Study of the Safety and Efficacy of APX3330 in Diabetic Retinopathy
ZETA-1: Diabetic Retinopathy Phase 2 Clinical Trial for APX3330:
View Clinical Trial
Completed
Safety and Efficacy of Ophthalmic Phentolamine Mesylate to Reverse Pharmacologically Induced Mydriasis
Reversal of Mydriasis Phase 2 Clinical Trial with Nyxol:
View Clinical Trial
Completed
Safety and Efficacy of Ophthalmic Phentolamine Mesylate in Glaucoma
Phase 2 Clinical Trial of Phentolamine Ophthalmic Solution 0.75% in Elderly Subjects with Glaucoma:
View Clinical Trial
Completed
Single Dose Study of Phentolamine Mesylate Eye Drops in Patients With Severe Night Vision Disturbances
Severe Night Vision Disturbance Single-Dose Phase 2 Clinical Trial with Nyxol:
View Clinical Trial
Completed
The Safety and Efficacy of Phentolamine Mesylate Ophthalmic Solution in Subjects With Severe Night Vision Disturbances
Night Vision Complaints Clinical Trial:
View Clinical Trial
Completed
A Study of APX3330 in Patients With Advanced Solid Tumors
APX3330 Cancer Phase 1 Clinical Trial:
View Clinical Trial
Completed
Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric Subjects
MIRA-4: Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis in Pediatric Subjects:
View Clinical Trial
Completed
Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)
MIRA-3:
View Clinical Trial
Completed
Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis
MIRA-2: Reversal of Mydriasis Phase 3 Clinical Trial for Nyxol:
View Clinical Trial
Completed
Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) in Subjects With Dim Light Vision Disturbances
LYNX-1: Dim Light Vision Disturbance Phase 3 Clinical Trial for Nyxol:
View Clinical Trial
Completed
Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia
VEGA-1: Presbyopia Phase 2 Clinical Trial for Nyxol with Low-Dose Pilocarpine:
View Clinical Trial